Güncel Patoloji Dergisi 2019, Cilt 3, Sayı 3
Granulomatosis with Polyangiitis in a Patient and Coincident Mucoepidermoid Carcinoma of the Lung: Case Report
Tuğba TOYRAN 1, Emine KILIÇ BAĞIR 2, Alper AVCI 3, Derya GÜMÜRDÜLÜ 2
1 Adana Şehir Eğitim ve Araştırma Hastanesi, Tıbbi Patoloji Anabilim Dalı, ADANA
2 Çukurova Üniversitesi Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, ADANA
3 Çukurova Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, ADANA
DOI : 10.5146/jcpath.2019.60 Granulomatosis with polyangiitis (Wegener"s granulomatosis) is a multisystemic disease associated with antineutrophilic cytoplasmic antibodies, characterized by necrotizing granulomatous inflammation of the upper and lower airways, focal glomerulonephritis and small-to-medium vascular vasculitis. Different clinical and histological findings seen in this disease. Specific symptoms can vary widely, depending on the affected organ.

A 40-year-old male patient was diagnosed as granulomatosis with polyangiitis with necrotic lesion in his right toe, impaired renal function tests, pulmonary hemorrhage / hemoptysis and increase in proteinase-3 antineutrophil cytoplasm antibody level.A rare mucoepidermoid carcinoma of the lung was detected during patient follow-up visits. There is no case reported in the literature regarding the coexistence of mucoepidermoid carcinoma and granulomatosis with polyangiitis. Anahtar Kelimeler : Granulomatosis with polyangiitis, Mucoepidermoid carcinoma, Lung