Güncel Patoloji Dergisi
2019, Cilt 3, Sayı 3
Mediastinal Cyst with Mullerian Differentiation: Hattori Cyst
1 Antalya Kepez Devlet Hastanesi, Patoloji Bölümü, ANTALYA
2 Akdeniz Üniversitesi Tıp Fakültesi, Radyoloji Anabilim Dalı, ANTALYA
3 Akdeniz Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, ANTALYA
4 Akdeniz Üniversitesi Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, ANTALYA
DOI : 10.5146/jcpath.2019.63 Aim: Mediastinal cyst with mullerian differentiation is a rare entity among primary congenital mediastinal cysts. This cyst is located in the posterior mediastinum. It was first described by Hattori in 2005 and named as Hattori cyst. Histopathologically, diagnosis is based on the presence of ciliated epithelium with mullerian differentiation. Typically, the cyst epithelium is positive with ER, PR, PAX8 and WT-1, and the stroma constituting the cyst wall is positive with ??-smooth muscle actin (?? SMA).
2 Akdeniz Üniversitesi Tıp Fakültesi, Radyoloji Anabilim Dalı, ANTALYA
3 Akdeniz Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, ANTALYA
4 Akdeniz Üniversitesi Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, ANTALYA
DOI : 10.5146/jcpath.2019.63 Aim: Mediastinal cyst with mullerian differentiation is a rare entity among primary congenital mediastinal cysts. This cyst is located in the posterior mediastinum. It was first described by Hattori in 2005 and named as Hattori cyst. Histopathologically, diagnosis is based on the presence of ciliated epithelium with mullerian differentiation. Typically, the cyst epithelium is positive with ER, PR, PAX8 and WT-1, and the stroma constituting the cyst wall is positive with ??-smooth muscle actin (?? SMA).
Case: Herein, we presented a 42-year-old female patient with paravertebral cystic lesion who was diagnosed as Hattori Cyst due to the mullerian origin of epithelium which was positive with ER, PR and WT-1.
Conclusion: The case is presented because of being a rare entity that should be kept in mind in the differential diagnosis of other mediastinal cysts.
Anahtar Kelimeler : Hattori, Mediastinal cyst, Mullerian differentiation