Materials and Methods: A retrospective analysis of nipple discharge cytology samples was performed between January 1, 2015 and December 31, 2016. Patients who underwent surgical excision after a nipple discharge cytology diagnosis of ?suggestive papillary lesions? were included the study. Cytologic slides were re-evaluated and graded for the morphologic features of three dimentional ductal groups.

Results: In the present study 25 patients (median age:46 years; range:26-81) with nipple discharge cytology were examined. Histopathologic findings showed 2 (8%) ductal carcinoma in situ, 6 (24%) intraductal papilloma, 2 (8%) atipical intraductal papilloma, 3 (12%) multiple intraductal papillomatosis, 1 (4%) nipple adenoma, 9 (36%) duct ectasia and 2 (8%) fibrocystic changes.

Conclusion: Three dimentional and papillary ductal groups were seen in both non-neoplastic and neoplastic breast lesions. The increasing number of groups and large, braching clusters had 50% and 57% sensitivity; and 55% and 64% specificity for neoplastic lesions, respectively. Anahtar Kelimeler : Nipple discharge, Papillary breast lesions, Cytology